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Generic Motrin 400 MG
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Motrin is a nonsteroidal anti-inflammatory drug available in both prescription and nonprescription forms. Prescription Motrin is used in adults for relief of the symptoms of rheumatoid arthritis and osteoarthritis, treatment of menstrual pain, and relief of mild to moderate pain. In children aged 6 months and older it can be given to reduce fever and relieve mild to moderate pain. It is also used to relieve the symptoms of juvenile arthritis.


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Brand name: Motrin
Generic name: Ibuprofen
Other brand name: Advil

Motrin IB tablets, caplets, and gelcaps; Children's Motrin Suspension; and Advil tablets and caplets are available without a prescription. Check the packages for uses, dosage, and other information on these products.
Most important fact about Motrin

You should have frequent checkups with your doctor if you take Motrin regularly. Ulcers or internal bleeding can occur without warning.
How should you take Motrin?

Your doctor may ask you to take Motrin with food or an antacid to avoid stomach upset. The suspension can be given with meals or milk if it upsets the stomach.

A drink of water or other fluid after taking a chewable tablet can help your body absorb the drug.

If you are using Motrin for arthritis, you should take it regularly, exactly as prescribed.
--If you miss a dose...
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage information...
Store at room temperature.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Motrin.
More common side effects may include:
Abdominal cramps or pain, abdominal discomfort, bloating and gas, constipation, diarrhea, dizziness, fluid retention and swelling, headache, heartburn, indigestion, itching, loss of appetite, nausea, nervousness, rash, ringing in ears, stomach pain, vomiting.
Why should Motrin not be prescribed?

If you are sensitive to or have ever had an allergic reaction to ibuprofen, aspirin, or similar drugs, such as Aleve and Naprosyn, or if you have had asthma attacks caused by aspirin or other drugs of this type, or if you have angioedema, a condition whose symptoms are skin eruptions, you should not take this medication.

Make sure that your doctor is aware of any drug reactions that you have experienced.
Special warnings about Motrin

Peptic ulcers and bleeding can occur without warning. Tell your doctor if you have bleeding or any other problems.

This drug should be used with caution if you have kidney or liver disease, or are severely dehydrated; it can cause liver or kidney inflammation or other problems in some people.

Do not take aspirin or any other anti-inflammatory medications while taking Motrin unless your doctor tells you to do so.

If you have a severe allergic reaction, seek medical help immediately.

Motrin may cause vision problems. If you experience any changes in your vision, inform your doctor.

Motrin may prolong bleeding time. If you are taking blood-thinning medication, this drug should be taken with caution.

This drug can cause water retention. It should be used with caution if you have high blood pressure or poor heart function.

Avoid the use of alcohol while taking this medication.

Motrin may mask the usual signs of infection or other diseases. Use with care in the presence of an existing infection.

If you have diabetes, remember that the suspension contains 1.5 grams of sucrose and 8 calories per teaspoonful.

Motrin chewable tablets contain phenylalanine. If you have a hereditary disease called phenylketonuria, you should be aware of this.
Possible food and drug interactions when taking Motrin

If Motrin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Motrin with the following:

Aspirin
Blood pressure medications known as ACE inhibitors, including Vasotec and Capoten
Blood-thinning drugs such as Coumadin
Diuretics such as Lasix and HydroDIURIL
Lithium (Lithonate)
Methotrexate (Rheumatrex)

Special information if you are pregnant or breastfeeding

The effects of ibuprofen during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Ibuprofen may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished.

Recommended dosage

ADULTS

Rheumatoid Arthritis and Osteoarthritis

The usual dosage is 1,200 to 3,200 milligrams per day divided into 3 or 4 doses. Your doctor will tailor the dose to your individual needs. Symptoms should be reduced within 2 weeks. Daily dosage should not be greater than 3,200 milligrams.

Mild to Moderate Pain

The usual dose is 400 milligrams every 4 to 6 hours as necessary.

Menstrual Pain

The usual dose is 400 milligrams every 4 hours as necessary. Begin treatment when symptoms first appear.

CHILDREN 6 MONTHS TO 12 YEARS OF AGE

Fever reduction

The recommended dose is 5 milligrams per 2.2 pounds of body weight if temperature is less than 102.5°F or 10 milligrams per 2.2 pounds of body weight if temperature is 102.5°F or greater. The fever should go down for 6 to 8 hours. Do not give the child more than 40 milligrams per 2.2 pounds of body weight in one day.

Mild to Moderate Pain

The usual dose is 10 milligrams per 2.2 pounds of body weight every 6 to 8 hours. Do not give the child more than 4 such doses per day.

Juvenile Arthritis

The usual dose is 30 to 40 milligrams daily per 2.2 pounds of body weight, divided into 3 or 4 doses. Some children may need only 20 milligrams daily per 2.2 pounds.
Overdosage

Any medication taken in excess can have serious consequences. An overdose of Motrin can be fatal. If you suspect an overdose, seek medical attention immediately.
Symptoms of Motrin overdose may include:
Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting
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